Lyophilized platelets: challenges and opportunities.

Flow Cytometric Measurement of CD41/CD61, CD42b Platelet Receptors and Platelet Factor 3 Activity in Lyophilized Infusible Platelet Membrane Preparation

Background: The short life time of human platelet units has led to a chronic shortage of fresh platelets in blood transfusion centers. Many approaches have been investigated experimentally to produce new hemostatically active platelet products that are capable of long term storage. Infusible platelet membrane (IPM) prepared from fresh or outdated human platelets have been developed as an altern...

International Journal of Drug Delivery

Saleh Nasiri Research Center of Iranian Blood Transfusion Organization (IBTO), Tehran, Iran. Tel: +98-218-860-1501-30, Fax: +98-218-860-1555, E-mail: [email protected] Abstract Human platelet concentrates are usually stored in blood banks for 5 days, after expiration date they are discarded. Human lyophilized platelet is one of the approaches to preserve the platelets for long time stor...

Preservation of hemostatic and structural properties of rehydrated lyophilized platelets: potential for long-term storage of dried platelets for transfusion.

Currently, therapeutic platelet concentrates can be stored for only 5 days. We have developed a procedure that permits long-term storage of fixed and lyophilized platelets that retain hemostatic properties after rehydration. These rehydrated lyophilized platelets (RL platelets) restore hemostasis in thrombocytopenic rats and become incorporated in the hemostatic plug of bleeding time wounds of ...

Proposing a model for entrepreneurship opportunities and challenges in online social networks in Iran

Human life has been affected by new communications in recent years. The development of cyberspace has led to businesses embracing social networks. The appearance of the cyberspace and features offered by information technology (IT) has provided hope, wishes, opportunities, and challenges for business owners. Organizations create opportunities for improving productivity, market share and value, ...

Review of Challenges and Opportunities Health Information Technology-based Art Therapy in Education and Treatment